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VI Simpósio Internacional de Oncologia Translacional e Pesquisa Clínica

Imagem do Evento: VI Simpósio Internacional de Oncologia Translacional e Pesquisa Clínica

    The Teaching and Research Institute (IEP) of Barretos Cancer Hospital harbors a Molecular Oncology Research Center (CPOM), Clinical Research Unity (UPC) and Master and PhD program in Oncology that performed a vast array of translational research studies, aiming to foster the development of precision medicine in our Institution. The CPOM is an advanced center for molecular oncology research with state-of-the art facilities and platforms in the field of cytogenetics, molecular genetics, molecular and cell biology. The UPC aims to conduct phase I, II and III clinical studies in oncology. Through the UPC, novel oncological treatments are available to patients, with new drugs, new combinations of drugs and / or new therapeutic approaches - developed in academic or private sponsorship. The UPC has become a reference center for conducting clinical trials in Brazil and Latin America.
   Therefore, in order to continue this mission of being at the forefront of knowledge, researchers, oncologists, residents, graduate students and other health professionals, the Barretos Cancer Hospital is organizing the VI International Symposium on Translational Oncology and Clinical Research, where key oncology topics are explored and updated. This event, organized by researchers and oncologists from Barretos Cancer Hospital, aim to promote discussion and interaction between the public and national and international researchers who develop their work in centers of excellence in various areas of oncology, which will contribute to the consolidation and improvement of translational medicine and clinical research in oncology.

Importance of the event

This event will be important to foster the discussion and interaction between the target public and nationally and internationally recognized researchers and physicians who develop their work in centers of excellence in the different areas of oncology research, which will contribute to the consolidation and upgrading of personalized medicine and clinical research in oncology.


09/22/17 (Friday)

07:30 am - 08:00 am – Registration

08:00 am - 08:10 am – Opening and Welcome.

Rui Manuel Reis, PhD (HCB, Barretos, Brazil)
Scientific Director

Edmundo Carvalho Mauad, MD, PhD (HCB, Barretos, Brazil)
Technical Diretor

08:10 am - 10:10 am | Session1

Hereditary Cancer and genetic risk factors

Discussion Leaders: Edenir Inez Palmero, PhD | Henrique Campos Galvão, MD. 

08:10 am – 08:40 am | Annotation and classification of variants of uncertain Clinical Significance: The BRCA1 and BRCA2 paradigm
Alvaro NA. Monteiro, PhD (H. Lee Moffitt Cancer Center & Reserach Institute, Florida, USA)

08:40 am  09:10 | Hereditary cancer and genetic risk factors
Rodrigo Guindalini, MD (ICESP, São Paulo, Brazil)

09:10 am – 09:40 | Molecular profile of hereditary breast cancer in Brazil
Patrícia Ashton Prolla, MD, PhD (UFRGS, Rio Grande do Sul, Brazil

09:40 am - 10:10 am | Discussion

10:10 am - 10:40 am | Coffee break and visit to the posters

10:40 am - 12:40 pm | Session 2

Early detection and cancer screening
Discussion Leaders:
Denise Peixoto Guimarães, MD, PhD | Ricardo Kalaf Mussi, MD, PhD.

10:40 am – 11:10 am | Are we ready to impement HPV test as primary screening for cervical cancer?
Luisa Lina Villa, PhD (ICESP, São Paulo, Brazil)

11:10 am – 11:40 Molecular profile of lung cancer for early detection strategies
Rui Manuel Reis, PhD (Barretos Cancer Hospital, Barretos, Brazil)

11:40 am – 12:10 Genomic Analysis of Colorectal Polyps in Hereditary High-Risk CRC Populations:  Opportunitiies for Prevention
Eduardo Vilar Sanchez, MD, PhD (MD Anderson Cancer Center, Houston, USA)

12:10 pm – 12:40 pm | Discussion

12:40 pm - 01:10 pm | Strategies for contamination prevention in cell culture laboratories.

Rodrigo Ribeiro da Silva, PhD (Eppendorf, São Paulo, São Paulo, Brazil)

1:10 pm - 01:40pm - Lunch

1:40 pm - 02:25 pm - Oral presentation of Best Abstracts

Discussion Leader: Luiz Fernando Lopes, MD, PhD / Jeremy Squiri, PhD.

1:40 pm – 1:50 pm | Molecular cloning of two phospholipases A2 from the Ectatomma opaciventre venonm gland for treatment of head and neck tumor.
Angela das Neves Oliveira, BS (Barretos Cancer Hospital).

1:50 pm – | 02:00 pm Methilation profile of tumor suppressor genes as biomarkers of cervical high-grade lesions. 
Caroline Domingues Rogeri, MS (Barretos Cancer Hospital)

02:00 pm – 02:10  | Evaluation of in Vitro and In Vivo Antitumor Efficacy of Hecane Partition from Annoma Crassiflora Mart on Human Cervical Cancer Cell Lines.
Ana Laura Vieira Alves, BS (Barretos Cancer Hospital)

01:10 pm – 01:25 pm | Discussion

02:25 pm - 04:25 pm | Session 3

Environmental factors and their role in cancer development

Discussion Leaders: Henrique Cesar Santejo Silveira, PhD / Fabiana de Lima Vazquez, PhD

02:25 pm – 02:55 pm | Using genetics to understad environmental and lifestyle causes of cancer
Paul Brennan, PhD (IARC, Lyon, France)

02:55 pm–03:25 pm | Mechanims of action of enviromental factors in upper aerodigestive tract tumors of brazilian patients
Luis Felipe Ribeiro Pinto, PhD (Instituto Nacional de Câncer - INCA)

03:25 pm – 03:55 pm | Biomarkers of Early Biological Effect: A critical tool in the study of environmental exposure to genotoxic agents. 

Stefano Bonassi, PhD (San Raffaele University, Rome, Italy)

03:55 pm – 04:25 pm | Discussion

04:25 pm - 06:25 pm | Session 4

Molecular biomarkers in translation oncology 

Discussion Leaders: Daniel Onofre Vidal, PhD / Márcia Maria C. Silveira, PhD

04:25 pm – 04:55 pm | Molecular Landscape of Brazilian Melanomas 
Adriane Feijó Evangelista, PhD

04:55 pm – 05:25 pm | Genomic profiling of solid tumors and cell free DNA: research and clinical aspects.
 Agda Karina Eterovic, PhD (MD Anderson Cancer Center, Houston, USA)

05:25 pm – 05:55 pm | Extracellular vesicles in Tumor Biology and Response to Therapy
Vilma Regina Martins, PhD (Hospital AC Camargo Cancer Center, São Paulo, Brazil)

05:55 pm – 06:25pm | Discussion

09/23/17 (Saturday)

07:30 am - 09:30 am | Session 5

Personalized Medicine

Discussion Leaders: Vinícius de Lima Vazquez, MD, PhD / Cristovam Scapulatempo Neto, MD, PhD

07:30 am – 08:00 am | Tumor heterogeneity: challenges and opportunities  
Andrew Futreal,  (MD Anderson Cancer Center, Houston, USA)

08:00 am – 08:30 am | The Tumor micro environment and its regulations.
Nelson Jen An Chao, MD, PhD (Duke Global Health Institute, Durham, USA).

08:30 am – 09:00 am | Translacional Medicine in Neuro-Oncology: Where are we going?
Luciano Neder Serafini, MD, PhD (Barretos Cancer Hospital, Barretos, Brazil)

09:00 am – 09:30 am | Discussion

09:30 am – 10:00 am | Coffe-break and visit to the posters.

10:00 am - 10:30 am | Techinical Lecture |  New technologies in cancer treatment

10:30 am - 12:00 pm | Session 6

Innovative approaches for cancer discovery and treatment.
Discussion Leaders:
Celine Marques Pinheiro, PhD / Matias Eliseo Melendez, PhD

10:30 am – 11:00 am | Exploiting biological therapies for treating gliomas.
Frederick F. Lang, MD (MD Anderson Cancer Center, Houston, USA)

11:00 am – 11:30 am | Cancer immunotherapy utilizing gene transfer
Bryan Eric Strauss, PhD (ICESP, São Paulo, Brazil)

11:30 am – 12:00 pm | Discussion

12:00 pm - 01:30 pm | Session 7

Drug development in clinical oncology
Discussion Leaders:
Pedro De Marchi, MD / Flávio Cárcano, MD

12:00 pm – 12:30 pm | Development of new drug candidates in Brazil: how to innovate?
Kerly Fernanda Mesquita Pasqualoto (Alchemy, São Paulo, Brazil)

12:30 pm – 01:00 pm | Amblyomin-X, research and development of a new antitumor molecule
Ana Marisa Chudzinski-Tavassi, PhD (Instituto Butantan, São Paulo Brazil)

01:00 pm – 01:30 pm | Discussion.

01:30 pm – 02:00 pm | Lunch  

02:00 pm - 03:30 pm | Session 8

Challenges for development of early phases studies in Brazil
Discussion Leaders: 
Luiz Eduardo Zucca, MD / Rachel Riechelmann, MD. PhD

02:00 pm – 02:30 pm | The development of clinical studies in the USA: what a long experience at the National Institutes of Heath can teach us
Phillip Scheinberg, MD (Beneficência Portuguesa de São Paulo, São Paulo, Brazil)

02:30 pm – 03:00 pm | Clinical studies: DECIT/SCTIE/MS vision and perspectives
Camile Giaretta Sachetti, PhD (DECIT/ Ministério da Saúde) 

03:00 pm – 03:30 pm | Discussion

03:30 pm - 03:45 pm | Awards to the best oral and poster presentation
Discussion Leader: Jeremy Squiri PhD | Luiz Fernando Lopes, PhD/ and Scientific Comission

03:30 pm – 03:45 pm | Closing Remarks.


Executive Organizers

José Humberto Tavares Guerreiro Fregnani
Luís Eduardo Rosa Zucca
Rui Manuel Reis

Scientific Organizers

Adhemar Longatto-Filho
Ana Carolina Carvalho
Adriane Evangelista Feijo
Celine Marques Pinheiro
Cristovam Scapulatempo Neto
Daniel Onofre Vidal
Edenir InesPalmero
Denise Guimarães
Fabiana Vazquez
Flávio Cárcano
Henrique Cesar Santejo Silveira
Letícia Ferro Leal
Luciano Neder
Luis Fernando Lopes
Márcia Maria Chiquitelli Marques Silveira
Matias Melendez
Pedro de Marchi
Pedro de Sousa
Sergio Serrano
Vinícius Vazquez

Commissioning committee

Ana Paula de Araújo
Carolina Sgorlon Jorgetto
Daniela Donadon
João Paulo Franco
Joyce Silva Pinto
Marcelo Nogueira Menezes





Professional and PhD – R$ 350,00

Post graduate students – R$ 250,00

Graduate Students – R$ 150,00

Collaborators at the Barretos Cancer Hospital - R$ 150,00

Cancellation deadline of  Inscription - seven days



Sub. Trabalho


Seleção dos resumos:

Todos os resumos submetidos serão avaliados pela comissão científica. Os candidatos selecionados serão convidados a apresentar seus trabalhos em formato de pôster durante a sessão de pôsteres. Três resumos serão selecionados para apresentações orais. Os resumos submetidos ao simpósio deverão ser fundamentados no tema do simpósio (oncologia translacional).


Critérios de seleção dos trabalhos:

  1. Originalidade científica, inovação, qualidade e relevância temática do trabalho ao tema do evento;
  2. Resumo conciso, clareza na apresentação das idéias, compreensível e com conclusões pertinentes.


Instruções para o envio de resumos:

Os resumos devem ser apresentados em inglês, letra no estilo Times New Roman, tamanho 12, espaçamento 1,5 e alinhamento Justificado.

O resumo deve incluir o Título, nome(s) e afiliação(ões) dos autores e deve ser estruturado, sendo dividido da seguinte forma: Introdução, Objetivos, Materiais e Métodos, Resultados e Conclusões. Deve ter no máximo 250 palavras (sem contar o Título, nomes e afiliações).


Instruções para a confecção de pôsteres:

O espaço destinado ao pôster será de 2 metros de altura por 1 metro de largura (na orientação retrato). Você pode preencher esse espaço como desejar, entretanto o tamanho recomendado para o seu cartaz é de 90 cm de largura e 120 cm de altura, na orientação retrato. Deverá conter alça ou cordinha para pendurar no local.

 Pelo menos um autor do trabalho deve estar inscrito no evento como um participante. As inscrições para o evento estão disponíveis em nosso site: (a definir).




O melhor pôster e a melhor apresentação oral serão pre

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