07:30 am - 08:00 am – Registration
08:00 am - 08:10 am – Opening and Welcome.
Rui Manuel Reis, PhD (HCB, Barretos, Brazil)
Edmundo Carvalho Mauad, MD, PhD (HCB, Barretos, Brazil)
08:10 am - 10:10 am | Session1
Hereditary Cancer and genetic risk factors
Discussion Leaders: Edenir Inez Palmero, PhD | Henrique Campos Galvão, MD.
08:10 am – 08:40 am | Annotation and classification of variants of uncertain Clinical Significance: The BRCA1 and BRCA2 paradigm
Alvaro NA. Monteiro, PhD (H. Lee Moffitt Cancer Center & Reserach Institute, Florida, USA)
08:40 am – 09:10 | Hereditary cancer and genetic risk factors
Rodrigo Guindalini, MD (ICESP, São Paulo, Brazil)
09:10 am – 09:40 | Molecular profile of hereditary breast cancer in Brazil
Patrícia Ashton Prolla, MD, PhD (UFRGS, Rio Grande do Sul, Brazil
09:40 am - 10:10 am | Discussion
10:10 am - 10:40 am | Coffee break and visit to the posters
10:40 am - 12:40 pm | Session 2
Early detection and cancer screening
Discussion Leaders: Denise Peixoto Guimarães, MD, PhD | Ricardo Kalaf Mussi, MD, PhD.
10:40 am – 11:10 am | Are we ready to impement HPV test as primary screening for cervical cancer?
Luisa Lina Villa, PhD (ICESP, São Paulo, Brazil)
11:10 am – 11:40 | Molecular profile of lung cancer for early detection strategies
Rui Manuel Reis, PhD (Barretos Cancer Hospital, Barretos, Brazil)
11:40 am – 12:10 | Genomic Analysis of Colorectal Polyps in Hereditary High-Risk CRC Populations: Opportunitiies for Prevention
Eduardo Vilar Sanchez, MD, PhD (MD Anderson Cancer Center, Houston, USA)
12:10 pm – 12:40 pm | Discussion
12:40 pm - 01:10 pm | Strategies for contamination prevention in cell culture laboratories.
Rodrigo Ribeiro da Silva, PhD (Eppendorf, São Paulo, São Paulo, Brazil)
1:10 pm - 01:40pm - Lunch
1:40 pm - 02:25 pm - Oral presentation of Best Abstracts
Discussion Leader: Luiz Fernando Lopes, MD, PhD / Jeremy Squiri, PhD.
1:40 pm – 1:50 pm | Molecular cloning of two phospholipases A2 from the Ectatomma opaciventre venonm gland for treatment of head and neck tumor.
Angela das Neves Oliveira, BS (Barretos Cancer Hospital).
1:50 pm – | 02:00 pm Methilation profile of tumor suppressor genes as biomarkers of cervical high-grade lesions.
Caroline Domingues Rogeri, MS (Barretos Cancer Hospital)
02:00 pm – 02:10 | Evaluation of in Vitro and In Vivo Antitumor Efficacy of Hecane Partition from Annoma Crassiflora Mart on Human Cervical Cancer Cell Lines.
Ana Laura Vieira Alves, BS (Barretos Cancer Hospital)
01:10 pm – 01:25 pm | Discussion
02:25 pm - 04:25 pm | Session 3
Environmental factors and their role in cancer development
Discussion Leaders: Henrique Cesar Santejo Silveira, PhD / Fabiana de Lima Vazquez, PhD
02:25 pm – 02:55 pm | Using genetics to understad environmental and lifestyle causes of cancer
Paul Brennan, PhD (IARC, Lyon, France)
02:55 pm–03:25 pm | Mechanims of action of enviromental factors in upper aerodigestive tract tumors of brazilian patients
Luis Felipe Ribeiro Pinto, PhD (Instituto Nacional de Câncer - INCA)
03:25 pm – 03:55 pm | Biomarkers of Early Biological Effect: A critical tool in the study of environmental exposure to genotoxic agents.
Stefano Bonassi, PhD (San Raffaele University, Rome, Italy)
03:55 pm – 04:25 pm | Discussion
04:25 pm - 06:25 pm | Session 4
Molecular biomarkers in translation oncology
Discussion Leaders: Daniel Onofre Vidal, PhD / Márcia Maria C. Silveira, PhD
04:25 pm – 04:55 pm | Molecular Landscape of Brazilian Melanomas
Adriane Feijó Evangelista, PhD
04:55 pm – 05:25 pm | Genomic profiling of solid tumors and cell free DNA: research and clinical aspects.
Agda Karina Eterovic, PhD (MD Anderson Cancer Center, Houston, USA)
05:25 pm – 05:55 pm | Extracellular vesicles in Tumor Biology and Response to Therapy
Vilma Regina Martins, PhD (Hospital AC Camargo Cancer Center, São Paulo, Brazil)
05:55 pm – 06:25pm | Discussion
07:30 am - 09:30 am | Session 5
Discussion Leaders: Vinícius de Lima Vazquez, MD, PhD / Cristovam Scapulatempo Neto, MD, PhD
07:30 am – 08:00 am | Tumor heterogeneity: challenges and opportunities
Andrew Futreal, (MD Anderson Cancer Center, Houston, USA)
08:00 am – 08:30 am | The Tumor micro environment and its regulations.
Nelson Jen An Chao, MD, PhD (Duke Global Health Institute, Durham, USA).
08:30 am – 09:00 am | Translacional Medicine in Neuro-Oncology: Where are we going?
Luciano Neder Serafini, MD, PhD (Barretos Cancer Hospital, Barretos, Brazil)
09:00 am – 09:30 am | Discussion
09:30 am – 10:00 am | Coffe-break and visit to the posters.
10:00 am - 10:30 am | Techinical Lecture | New technologies in cancer treatment
10:30 am - 12:00 pm | Session 6
Innovative approaches for cancer discovery and treatment.
Discussion Leaders: Celine Marques Pinheiro, PhD / Matias Eliseo Melendez, PhD
10:30 am – 11:00 am | Exploiting biological therapies for treating gliomas.
Frederick F. Lang, MD (MD Anderson Cancer Center, Houston, USA)
11:00 am – 11:30 am | Cancer immunotherapy utilizing gene transfer
Bryan Eric Strauss, PhD (ICESP, São Paulo, Brazil)
11:30 am – 12:00 pm | Discussion
12:00 pm - 01:30 pm | Session 7
Drug development in clinical oncology
Discussion Leaders: Pedro De Marchi, MD / Flávio Cárcano, MD
12:00 pm – 12:30 pm | Development of new drug candidates in Brazil: how to innovate?
Kerly Fernanda Mesquita Pasqualoto (Alchemy, São Paulo, Brazil)
12:30 pm – 01:00 pm | Amblyomin-X, research and development of a new antitumor molecule
Ana Marisa Chudzinski-Tavassi, PhD (Instituto Butantan, São Paulo Brazil)
01:00 pm – 01:30 pm | Discussion.
01:30 pm – 02:00 pm | Lunch
02:00 pm - 03:30 pm | Session 8
Challenges for development of early phases studies in Brazil
Discussion Leaders: Luiz Eduardo Zucca, MD / Rachel Riechelmann, MD. PhD
02:00 pm – 02:30 pm | The development of clinical studies in the USA: what a long experience at the National Institutes of Heath can teach us
Phillip Scheinberg, MD (Beneficência Portuguesa de São Paulo, São Paulo, Brazil)
02:30 pm – 03:00 pm | Clinical studies: DECIT/SCTIE/MS vision and perspectives
Camile Giaretta Sachetti, PhD (DECIT/ Ministério da Saúde)
03:00 pm – 03:30 pm | Discussion
03:30 pm - 03:45 pm | Awards to the best oral and poster presentation
Discussion Leader: Jeremy Squiri PhD | Luiz Fernando Lopes, PhD/ and Scientific Comission
03:30 pm – 03:45 pm | Closing Remarks.